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LMNA

2019-08-21 15:14:59 百科

LMNA

核纤层蛋白 A/C(英语:Lamin A/C)是由人类基因LMNA编码的蛋白质,属于核纤层蛋白家族。

核纤层蛋白 A/C(英语:Lamin A/C)是由人类基因LMNA编码的蛋白质,属于核纤层蛋白家族。
核纤层蛋白 A/C
Lamin A/C

PDBrendering based on 1ifr.
有效结构
PDB直系同源检索:PDBe,RCSB
[隐藏]PDB查询代码列表
1IFR,1IVT,1X8Y,2XV5,2YPT,3GEF,3V4Q,3V4W,3V5B
[隐藏]PDB查询代码列表
1IFR,1IVT,1X8Y,2XV5,2YPT,3GEF,3V4Q,3V4W,3V5B
代号
LMNA; CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; PRO1
扩展标识
遗传学:150330鼠基因:96794同源基因:41321ChEMBL:1293235GeneCards:LMNA Gene
[隐藏]基因本体论描述
分子功能·structural molecule activity
·protein binding
细胞成分·nucleus
·nuclear envelope
·lamin filament
·nuclear lamina
·nucleoplasm
·cytoplasm
·cytosol
·intermediate filament
·perinuclear region of cytoplasm
生物过程·M phase of mitotic cell cycle
·mitotic prophase
·mitotic anaphase
·mitotic cell cycle
·apoptotic process
·cellular component disassembly involved in execution phase of apoptosis
·activation of signaling protein activity involved in unfolded protein response
·mitotic nuclear envelope disassembly
·mitotic nuclear envelope reassembly
·muscle organ development
·regulation of cell migration
·establishment or maintenance of microtubule cytoskeleton polarity
·endoplasmic reticulum unfolded protein response
·protein localization to nucleus
·sterol regulatory element binding protein import into nucleus
·regulation of apoptotic process
·cellular protein metabolic process
·ventricular cardiac muscle cell development
·cellular response to hypoxia
·positive regulation of cell aging
Sources:Amigo/QuickGO
更多表达数据
物种
人类
鼠类
Entrez
4000
16905
Ensembl
ENSG00000160789
ENSMUSG00000028063
UniProt
P02545
P48678
mRNA序列
NM_001257374
NM_001002011
蛋白序列
NP_001244303
NP_001002011
基因位置
Chr 1:
156.05 – 156.11 Mb
Chr 3:
88.48 – 88.51 Mb
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